M677-0725 Screening compound: N~1~-(4-fluorophenyl)-4-{4-[2-(propionylamino)ethyl]-1,3-thiazol-2-yl}tetrahydro-1(2H)-pyridinecarboxamide

M677-0725 Screening compound: N~1~-(4-fluorophenyl)-4-{4-[2-(propionylamino)ethyl]-1,3-thiazol-2-yl}tetrahydro-1(2H)-pyridinecarboxamide
M677-0725 Screening compound: N~1~-(4-fluorophenyl)-4-{4-[2-(propionylamino)ethyl]-1,3-thiazol-2-yl}tetrahydro-1(2H)-pyridinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M677-0725
N~1~-(4-fluorophenyl)-4-{4-[2-(propionylamino)ethyl]-1,3-thiazol-2-yl}tetrahydro-1(2H)-pyridinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M677-0725

Molecular Formula

C20H25FN4O2S (C20 H25 FN4 O2 S)

Compound Name

N~1~-(4-fluorophenyl)-4-{4-[2-(propionylamino)ethyl]-1,3-thiazol-2-yl}tetrahydro-1(2H)-pyridinecarboxamide

IUPAC name

n/a

SMILES

CCC(NCCc1csc(C(CC2)CCN2C(Nc(cc2)ccc2F)=O)n1)=O

InChI

InChI=1S/C20H25FN4O2S/c1-2-18(26)22-10-7-17-13-28-19(23-17)14-8-11-25(12-9-14)20(27)24-16-5-3-15(21)4-6-16/h3-6,13-14H,2,7-12H2,1H3,(H,22,26)(H,24,27)

InChI Key

AEQPQLYNSRHWPJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642457

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.580

Distribution Coefficient, logD

2.580

Water Solubility, LogSw

-3.00

Polar Surface Area

60.250

Acid Dissociation Constant (pKa)

12.23

Base Dissociation Constant (pKb)

3.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.00

M677-0725 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Antibacterial Compounds Library (13827 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with M677-0725 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M677-0725?
Check Price and Availability of M677-0725, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M677-0725 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M677-0725
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M677-0725
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M677-0725 available by request