M677-0771 Screening compound: N-cyclopentyl-4-{4-[2-(2-methylpropanamido)ethyl]-1,3-thiazol-2-yl}piperidine-1-carboxamide

M677-0771 Screening compound: N-cyclopentyl-4-{4-[2-(2-methylpropanamido)ethyl]-1,3-thiazol-2-yl}piperidine-1-carboxamide
M677-0771 Screening compound: N-cyclopentyl-4-{4-[2-(2-methylpropanamido)ethyl]-1,3-thiazol-2-yl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M677-0771
N-cyclopentyl-4-{4-[2-(2-methylpropanamido)ethyl]-1,3-thiazol-2-yl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M677-0771

Molecular Formula

C20H32N4O2S (C20 H32 N4 O2 S)

Compound Name

N-cyclopentyl-4-{4-[2-(2-methylpropanamido)ethyl]-1,3-thiazol-2-yl}piperidine-1-carboxamide

IUPAC name

N-cyclopentyl-4-{4-[2-(2-methylpropanamido)ethyl]-13-thiazol-2-yl}piperidine-1-carboxamide

SMILES

CC(C)C(NCCc1csc(C(CC2)CCN2C(NC2CCCC2)=O)n1)=O

InChI

InChI=1S/C20H32N4O2S/c1-14(2)18(25)21-10-7-17-13-27-19(22-17)15-8-11-24(12-9-15)20(26)23-16-5-3-4-6-16/h13-16H,3-12H2,1-2H3,(H,21,25)(H,23,26)

InChI Key

GMWKFDCWAJVDMB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27551139

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.986

Distribution Coefficient, logD

2.986

Water Solubility, LogSw

-3.19

Polar Surface Area

61.877

Acid Dissociation Constant (pKa)

14.66

Base Dissociation Constant (pKb)

3.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

75.00

M677-0771 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Cyclic compounds
  • Mimetics
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with M677-0771 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M677-0771?
Check Price and Availability of M677-0771, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M677-0771 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M677-0771
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M677-0771
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M677-0771 available by request