M678-0475 Screening compound: N-[2-(2-{1-[(1-METHYL-1H-PYRAZOL-5-YL)CARBONYL]-3-PIPERIDYL}-1,3-THIAZOL-4-YL)ETHYL]-1-CYCLOPROPANECARBOXAMIDE

M678-0475 Screening compound: N-[2-(2-{1-[(1-METHYL-1H-PYRAZOL-5-YL)CARBONYL]-3-PIPERIDYL}-1,3-THIAZOL-4-YL)ETHYL]-1-CYCLOPROPANECARBOXAMIDE
M678-0475 Screening compound: N-[2-(2-{1-[(1-METHYL-1H-PYRAZOL-5-YL)CARBONYL]-3-PIPERIDYL}-1,3-THIAZOL-4-YL)ETHYL]-1-CYCLOPROPANECARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound M678-0475
N-[2-(2-{1-[(1-METHYL-1H-PYRAZOL-5-YL)CARBONYL]-3-PIPERIDYL}-1,3-THIAZOL-4-YL)ETHYL]-1-CYCLOPROPANECARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M678-0475

Molecular Formula

C19H25N5O2S (C19 H25 N5 O2 S)

Compound Name

N-[2-(2-{1-[(1-METHYL-1H-PYRAZOL-5-YL)CARBONYL]-3-PIPERIDYL}-1,3-THIAZOL-4-YL)ETHYL]-1-CYCLOPROPANECARBOXAMIDE

IUPAC name

N-(2-{2-[1-(1-methyl-1H-pyrazole-5-carbonyl)piperidin-3-yl]-13-thiazol-4-yl}ethyl)cyclopropanecarboxamide

SMILES

Cn1nccc1C(N(CCC1)CC1c1nc(CCNC(C2CC2)=O)cs1)=O

InChI

InChI=1S/C19H25N5O2S/c1-23-16(7-9-21-23)19(26)24-10-2-3-14(11-24)18-22-15(12-27-18)6-8-20-17(25)13-4-5-13/h7,9,12-14H,2-6,8,10-11H2,1H3,(H,20,25)/t14-/m0/s1

InChI Key

QOFCZELSNAVBKU-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD27551360

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.219

Distribution Coefficient, logD

1.219

Water Solubility, LogSw

-2.12

Polar Surface Area

65.478

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

3.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

57.90

M678-0475 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M678-0475 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M678-0475?
Check Price and Availability of M678-0475, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M678-0475 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M678-0475
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M678-0475
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M678-0475 available by request