M714-0159 Screening compound: N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinolin-8-yl}acetamide

M714-0159 Screening compound: N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinolin-8-yl}acetamide
M714-0159 Screening compound: N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinolin-8-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M714-0159
N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinolin-8-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M714-0159

Molecular Formula

C21H21N5O2 (C21 H21 N5 O2)

Compound Name

N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinolin-8-yl}acetamide

IUPAC name

N-{4-[4-(pyridin-2-yl)piperazine-1-carbonyl]quinolin-8-yl}acetamide

SMILES

CC(Nc1c2nccc(C(N(CC3)CCN3c3ncccc3)=O)c2ccc1)=O

InChI

InChI=1S/C21H21N5O2/c1-15(27)24-18-6-4-5-16-17(8-10-23-20(16)18)21(28)26-13-11-25(12-14-26)19-7-2-3-9-22-19/h2-10H,11-14H2,1H3,(H,24,27)

InChI Key

VOYGSUDJRHPUIA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27551981

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.933

Distribution Coefficient, logD

1.925

Water Solubility, LogSw

-2.73

Polar Surface Area

60.756

Acid Dissociation Constant (pKa)

11.19

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

M714-0159 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with M714-0159 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M714-0159?
Check Price and Availability of M714-0159, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M714-0159 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M714-0159
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M714-0159
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M714-0159 available by request