M715-0118 Screening compound: 8-{4-[6-(piperidin-1-yl)pyridin-3-yl]benzoyl}-1,4-dioxa-8-azaspiro[4.5]decane

M715-0118 Screening compound: 8-{4-[6-(piperidin-1-yl)pyridin-3-yl]benzoyl}-1,4-dioxa-8-azaspiro[4.5]decane
M715-0118 Screening compound: 8-{4-[6-(piperidin-1-yl)pyridin-3-yl]benzoyl}-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound M715-0118
8-{4-[6-(piperidin-1-yl)pyridin-3-yl]benzoyl}-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M715-0118

Molecular Formula

C24H29N3O3 (C24 H29 N3 O3)

Compound Name

8-{4-[6-(piperidin-1-yl)pyridin-3-yl]benzoyl}-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-{4-[6-(piperidin-1-yl)pyridin-3-yl]benzoyl}-14-dioxa-8-azaspiro[4.5]decane

SMILES

O=C(c(cc1)ccc1-c(cc1)cnc1N1CCCCC1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C24H29N3O3/c28-23(27-14-10-24(11-15-27)29-16-17-30-24)20-6-4-19(5-7-20)21-8-9-22(25-18-21)26-12-2-1-3-13-26/h4-9,18H,1-3,10-17H2

InChI Key

PDHGFRVQUYYDOT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29019181

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

407.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.577

Distribution Coefficient, logD

3.569

Water Solubility, LogSw

-3.37

Polar Surface Area

43.105

Acid Dissociation Constant (pKa)

24.18

Base Dissociation Constant (pKb)

5.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

M715-0118 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

CNS BBB Library (22607 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M715-0118 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M715-0118?
Check Price and Availability of M715-0118, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M715-0118 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M715-0118
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M715-0118
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M715-0118 available by request