M728-1581 Screening compound: 1-(5-methylthiophene-2-carbonyl)-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]piperidine

M728-1581 Screening compound: 1-(5-methylthiophene-2-carbonyl)-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]piperidine
M728-1581 Screening compound: 1-(5-methylthiophene-2-carbonyl)-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M728-1581
1-(5-methylthiophene-2-carbonyl)-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M728-1581

Molecular Formula

C20H21N3O2S (C20 H21 N3 O2 S)

Compound Name

1-(5-methylthiophene-2-carbonyl)-4-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]piperidine

IUPAC name

1-(5-methylthiophene-2-carbonyl)-4-[(5-phenyl-134-oxadiazol-2-yl)methyl]piperidine

SMILES

Cc1ccc(C(N2CCC(Cc3nnc(-c4ccccc4)o3)CC2)=O)s1

InChI

InChI=1S/C20H21N3O2S/c1-14-7-8-17(26-14)20(24)23-11-9-15(10-12-23)13-18-21-22-19(25-18)16-5-3-2-4-6-16/h2-8,15H,9-13H2,1H3

InChI Key

VNSCIDDSHLISJX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27552128

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.217

Distribution Coefficient, logD

4.217

Water Solubility, LogSw

-4.17

Polar Surface Area

47.815

Acid Dissociation Constant (pKa)

26.00

Base Dissociation Constant (pKb)

-0.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

M728-1581 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M728-1581 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M728-1581?
Check Price and Availability of M728-1581, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M728-1581 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M728-1581
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M728-1581
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M728-1581 available by request