M734-0178 Screening compound: 1-(2-methoxybenzoyl)-4-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

M734-0178 Screening compound: 1-(2-methoxybenzoyl)-4-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine
M734-0178 Screening compound: 1-(2-methoxybenzoyl)-4-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M734-0178
1-(2-methoxybenzoyl)-4-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M734-0178

Molecular Formula

C25H30N2O4 (C25 H30 N2 O4)

Compound Name

1-(2-methoxybenzoyl)-4-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

IUPAC name

1-(2-methoxybenzoyl)-4-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

SMILES

COc(cccc1)c1C(N1CCC(COc(cccc2)c2C(N2CCCC2)=O)CC1)=O

InChI

InChI=1S/C25H30N2O4/c1-30-22-10-4-2-8-20(22)24(28)27-16-12-19(13-17-27)18-31-23-11-5-3-9-21(23)25(29)26-14-6-7-15-26/h2-5,8-11,19H,6-7,12-18H2,1H3

InChI Key

XBPISXMWMOMHPA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27552183

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.486

Distribution Coefficient, logD

3.486

Water Solubility, LogSw

-3.85

Polar Surface Area

48.846

Acid Dissociation Constant (pKa)

25.84

Base Dissociation Constant (pKb)

-1.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

M734-0178 in Drug Discovery

Included in Screening Libraries

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M734-0178 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M734-0178?
Check Price and Availability of M734-0178, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M734-0178 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M734-0178
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M734-0178
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M734-0178 available by request