M734-0469 Screening compound: N-CYCLOPROPYL-2-{[1-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)-4-PIPERIDYL]METHOXY}BENZAMIDE

M734-0469 Screening compound: N-CYCLOPROPYL-2-{[1-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)-4-PIPERIDYL]METHOXY}BENZAMIDE
M734-0469 Screening compound: N-CYCLOPROPYL-2-{[1-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)-4-PIPERIDYL]METHOXY}BENZAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound M734-0469
N-CYCLOPROPYL-2-{[1-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)-4-PIPERIDYL]METHOXY}BENZAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M734-0469

Molecular Formula

C25H28N2O5 (C25 H28 N2 O5)

Compound Name

N-CYCLOPROPYL-2-{[1-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)-4-PIPERIDYL]METHOXY}BENZAMIDE

IUPAC name

n/a

SMILES

O=C(C1Oc(cccc2)c2OC1)N1CCC(COc(cccc2)c2C(NC2CC2)=O)CC1

InChI

InChI=1S/C25H28N2O5/c28-24(26-18-9-10-18)19-5-1-2-6-20(19)30-15-17-11-13-27(14-12-17)25(29)23-16-31-21-7-3-4-8-22(21)32-23/h1-8,17-18,23H,9-16H2,(H,26,28)/t23-/m0/s1

InChI Key

QBBBFCLLFNINCS-QHCPKHFHSA-N

MDL Number (MFCD)

MFCD27552250

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.807

Distribution Coefficient, logD

3.807

Water Solubility, LogSw

-4.36

Polar Surface Area

64.108

Acid Dissociation Constant (pKa)

11.06

Base Dissociation Constant (pKb)

-0.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

M734-0469 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M734-0469 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M734-0469?
Check Price and Availability of M734-0469, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M734-0469 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M734-0469
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M734-0469
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M734-0469 available by request