M735-0958 Screening compound: 1-[(4-fluorophenyl)methyl]-3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

M735-0958 Screening compound: 1-[(4-fluorophenyl)methyl]-3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidine
M735-0958 Screening compound: 1-[(4-fluorophenyl)methyl]-3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M735-0958
1-[(4-fluorophenyl)methyl]-3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M735-0958

Molecular Formula

C25H31FN2O2 (C25 H31 FN2 O2)

Compound Name

1-[(4-fluorophenyl)methyl]-3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

IUPAC name

1-[(4-fluorophenyl)methyl]-3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

SMILES

O=C(c(cccc1)c1OCC1CN(Cc(cc2)ccc2F)CCC1)N1CCCCC1

InChI

InChI=1S/C25H31FN2O2/c26-22-12-10-20(11-13-22)17-27-14-6-7-21(18-27)19-30-24-9-3-2-8-23(24)25(29)28-15-4-1-5-16-28/h2-3,8-13,21H,1,4-7,14-19H2/t21-/m0/s1

InChI Key

KJLRLQIMCSXZKD-NRFANRHFSA-N

MDL Number (MFCD)

MFCD29004420

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.53

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.306

Distribution Coefficient, logD

3.420

Water Solubility, LogSw

-4.52

Polar Surface Area

27.867

Acid Dissociation Constant (pKa)

24.91

Base Dissociation Constant (pKb)

8.22

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

48.00

M735-0958 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

MEF2-HDAC (class II) Modulators Library (5147 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Female
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • Epigenetic
Targets:
  • GPCR
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M735-0958 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M735-0958?
Check Price and Availability of M735-0958, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M735-0958 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M735-0958
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M735-0958
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M735-0958 available by request