M735-0967 Screening compound: 5-[(3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]-1H-indole

M735-0967 Screening compound: 5-[(3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]-1H-indole
M735-0967 Screening compound: 5-[(3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound M735-0967
5-[(3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M735-0967

Molecular Formula

C27H33N3O2 (C27 H33 N3 O2)

Compound Name

5-[(3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]-1H-indole

IUPAC name

5-[(3-{[2-(piperidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]-1H-indole

SMILES

O=C(c(cccc1)c1OCC1CN(Cc(cc2)cc3c2[nH]cc3)CCC1)N1CCCCC1

InChI

InChI=1S/C27H33N3O2/c31-27(30-15-4-1-5-16-30)24-8-2-3-9-26(24)32-20-22-7-6-14-29(19-22)18-21-10-11-25-23(17-21)12-13-28-25/h2-3,8-13,17,22,28H,1,4-7,14-16,18-20H2/t22-/m0/s1

InChI Key

QOCFTRLMLLCFCS-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD31982677

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.369

Distribution Coefficient, logD

3.566

Water Solubility, LogSw

-4.27

Polar Surface Area

37.648

Acid Dissociation Constant (pKa)

18.61

Base Dissociation Constant (pKb)

8.13

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.44

M735-0967 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Proline Kinase Library (2105 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with M735-0967 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M735-0967?
Check Price and Availability of M735-0967, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M735-0967 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M735-0967
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M735-0967
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M735-0967 available by request