M735-1171 Screening compound: 2-fluoro-4-[(3-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]phenol

M735-1171 Screening compound: 2-fluoro-4-[(3-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]phenol
M735-1171 Screening compound: 2-fluoro-4-[(3-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound M735-1171
2-fluoro-4-[(3-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M735-1171

Molecular Formula

C24H29FN2O3 (C24 H29 FN2 O3)

Compound Name

2-fluoro-4-[(3-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]phenol

IUPAC name

2-fluoro-4-[(3-{[2-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidin-1-yl)methyl]phenol

SMILES

Oc(ccc(CN1CC(COc(cccc2)c2C(N2CCCC2)=O)CCC1)c1)c1F

InChI

InChI=1S/C24H29FN2O3/c25-21-14-18(9-10-22(21)28)15-26-11-5-6-19(16-26)17-30-23-8-2-1-7-20(23)24(29)27-12-3-4-13-27/h1-2,7-10,14,19,28H,3-6,11-13,15-17H2/t19-/m0/s1

InChI Key

XKZBCCSQAOAGGR-IBGZPJMESA-N

MDL Number (MFCD)

MFCD31983044

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.671

Distribution Coefficient, logD

2.892

Water Solubility, LogSw

-3.88

Polar Surface Area

44.781

Acid Dissociation Constant (pKa)

8.65

Base Dissociation Constant (pKb)

8.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

45.83

M735-1171 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M735-1171 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M735-1171?
Check Price and Availability of M735-1171, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M735-1171 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M735-1171
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M735-1171
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M735-1171 available by request