M735-1298 Screening compound: 2-({1-[(2-chloroquinolin-3-yl)methyl]piperidin-3-yl}methoxy)-N-cyclopropylbenzamide

M735-1298 Screening compound: 2-({1-[(2-chloroquinolin-3-yl)methyl]piperidin-3-yl}methoxy)-N-cyclopropylbenzamide
M735-1298 Screening compound: 2-({1-[(2-chloroquinolin-3-yl)methyl]piperidin-3-yl}methoxy)-N-cyclopropylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M735-1298
2-({1-[(2-chloroquinolin-3-yl)methyl]piperidin-3-yl}methoxy)-N-cyclopropylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M735-1298

Molecular Formula

C26H28ClN3O2 (C26 H28 ClN3 O2)

Compound Name

2-({1-[(2-chloroquinolin-3-yl)methyl]piperidin-3-yl}methoxy)-N-cyclopropylbenzamide

IUPAC name

2-({1-[(2-chloroquinolin-3-yl)methyl]piperidin-3-yl}methoxy)-N-cyclopropylbenzamide

SMILES

O=C(c(cccc1)c1OCC1CN(Cc2cc3ccccc3nc2Cl)CCC1)NC1CC1

InChI

InChI=1S/C26H28ClN3O2/c27-25-20(14-19-7-1-3-9-23(19)29-25)16-30-13-5-6-18(15-30)17-32-24-10-4-2-8-22(24)26(31)28-21-11-12-21/h1-4,7-10,14,18,21H,5-6,11-13,15-17H2,(H,28,31)/t18-/m0/s1

InChI Key

PJKPKHONDWARFU-SFHVURJKSA-N

MDL Number (MFCD)

MFCD29004518

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.041

Distribution Coefficient, logD

4.876

Water Solubility, LogSw

-5.18

Polar Surface Area

44.656

Acid Dissociation Constant (pKa)

11.06

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

38.50

M735-1298 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Eccentric PPI Library (11937 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M735-1298 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M735-1298?
Check Price and Availability of M735-1298, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M735-1298 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M735-1298
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M735-1298
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M735-1298 available by request