M735-1437 Screening compound: N-cyclopropyl-2-[(1-{1,4-dioxaspiro[4.5]decan-8-yl}piperidin-3-yl)methoxy]benzamide

M735-1437 Screening compound: N-cyclopropyl-2-[(1-{1,4-dioxaspiro[4.5]decan-8-yl}piperidin-3-yl)methoxy]benzamide
M735-1437 Screening compound: N-cyclopropyl-2-[(1-{1,4-dioxaspiro[4.5]decan-8-yl}piperidin-3-yl)methoxy]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M735-1437
N-cyclopropyl-2-[(1-{1,4-dioxaspiro[4.5]decan-8-yl}piperidin-3-yl)methoxy]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M735-1437

Molecular Formula

C24H34N2O4 (C24 H34 N2 O4)

Compound Name

N-cyclopropyl-2-[(1-{1,4-dioxaspiro[4.5]decan-8-yl}piperidin-3-yl)methoxy]benzamide

IUPAC name

N-cyclopropyl-2-[(1-{14-dioxaspiro[4.5]decan-8-yl}piperidin-3-yl)methoxy]benzamide

SMILES

O=C(c(cccc1)c1OCC(CCC1)CN1C(CC1)CCC11OCCO1)NC1CC1

InChI

InChI=1S/C24H34N2O4/c27-23(25-19-7-8-19)21-5-1-2-6-22(21)28-17-18-4-3-13-26(16-18)20-9-11-24(12-10-20)29-14-15-30-24/h1-2,5-6,18-20H,3-4,7-17H2,(H,25,27)/t18-/m0/s1

InChI Key

BXBMBQBYRPYATA-SFHVURJKSA-N

MDL Number (MFCD)

MFCD29018222

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.342

Distribution Coefficient, logD

0.849

Water Solubility, LogSw

-3.98

Polar Surface Area

49.678

Acid Dissociation Constant (pKa)

11.06

Base Dissociation Constant (pKb)

9.89

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

70.83

M735-1437 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Eccentric PPI Library (11937 compounds)

GPCR Targeted Library (31838 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with M735-1437 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M735-1437?
Check Price and Availability of M735-1437, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M735-1437 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M735-1437
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M735-1437
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M735-1437 available by request