M735-1643 Screening compound: 3-(3-{[2-(morpholine-4-carbonyl)phenoxy]methyl}piperidine-1-carbonyl)-1H-indazole
Chemical Structure Depiction of ChemDiv screening compound M735-1643
3-(3-{[2-(morpholine-4-carbonyl)phenoxy]methyl}piperidine-1-carbonyl)-1H-indazole
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
M735-1643
Molecular Formula
C25H28N4O4 (C25 H28 N4 O4)
Compound Name
3-(3-{[2-(morpholine-4-carbonyl)phenoxy]methyl}piperidine-1-carbonyl)-1H-indazole
IUPAC name
3-(3-{[2-(morpholine-4-carbonyl)phenoxy]methyl}piperidine-1-carbonyl)-1H-indazole
SMILES
O=C(c1n[nH]c2c1cccc2)N1CC(COc(cccc2)c2C(N2CCOCC2)=O)CCC1
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
448.52
Hydrogen Bond Acceptors Count
7.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
7.00
Number of Nitrogen and Oxygen Atoms
8
Partition Coefficient, logP
2.720
Distribution Coefficient, logD
2.720
Water Solubility, LogSw
-3.49
Polar Surface Area
71.938
Acid Dissociation Constant (pKa)
14.84
Base Dissociation Constant (pKb)
-0.99
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
40.00
M735-1643 in Drug Discovery
Included in Screening Libraries
Anti-Inflammatory Library (24602 compounds)
Antiviral Library (67538 compounds)
Bcl2-PPI Inhibitors Library (12246 compounds)
300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)
GPCR Targeted Library (31838 compounds)
PI3K-Targeted Library (17255 compounds)
PPI Helix Turn 3D-Mimetics Library (71298 compounds)
PPI Inhibitors Tripeptide Mimetics (23972 compounds)
Protein Kinases Inhibitors Library (36801 compounds)
Protein-Protein Interaction Library (218420 compounds)
Alpha-Helix Mimetics Library (25899 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
Included in 1.7M Stock Database
- Immune system
- Antiviral
- Infections
- Immune system
- Cancer
- Hemic and lymphatic
- Musculoskeletal
- Respiratory tract
- Nervous system
- Congenital
- Skin
- Metabolic
- Endocrine
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Male
- Female
- Hemic and lymphatic
- Skin
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Nervous system
- Hemic and lymphatic
- Cardiovascular
- PPI modulators
- Receptor's ligands
- PPI modulators
- PPI modulators
- PPI modulators
- PPI modulators
- GPCR
- Kinases
- Kinases
- Mimetics
- Mimetics
- Mimetics
- Cyclic compounds
References: we are preparing a list of scientific research reports with M735-1643 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)