M739-0183 Screening compound: 1-(4-chlorobenzoyl)-2-{[4-(pyrrolidine-1-carbonyl)phenoxy]methyl}pyrrolidine

M739-0183 Screening compound: 1-(4-chlorobenzoyl)-2-{[4-(pyrrolidine-1-carbonyl)phenoxy]methyl}pyrrolidine
M739-0183 Screening compound: 1-(4-chlorobenzoyl)-2-{[4-(pyrrolidine-1-carbonyl)phenoxy]methyl}pyrrolidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M739-0183
1-(4-chlorobenzoyl)-2-{[4-(pyrrolidine-1-carbonyl)phenoxy]methyl}pyrrolidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M739-0183

Molecular Formula

C23H25ClN2O3 (C23 H25 ClN2 O3)

Compound Name

1-(4-chlorobenzoyl)-2-{[4-(pyrrolidine-1-carbonyl)phenoxy]methyl}pyrrolidine

IUPAC name

1-(4-chlorobenzoyl)-2-{[4-(pyrrolidine-1-carbonyl)phenoxy]methyl}pyrrolidine

SMILES

O=C(c(cc1)ccc1OCC(CCC1)N1C(c(cc1)ccc1Cl)=O)N1CCCC1

InChI

InChI=1S/C23H25ClN2O3/c24-19-9-5-18(6-10-19)23(28)26-15-3-4-20(26)16-29-21-11-7-17(8-12-21)22(27)25-13-1-2-14-25/h5-12,20H,1-4,13-16H2/t20-/m1/s1

InChI Key

WRSLCDDFTRNDOS-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD27552291

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.92

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.695

Distribution Coefficient, logD

3.695

Water Solubility, LogSw

-4.24

Polar Surface Area

41.141

Acid Dissociation Constant (pKa)

24.83

Base Dissociation Constant (pKb)

-3.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

M739-0183 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M739-0183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M739-0183?
Check Price and Availability of M739-0183, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M739-0183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M739-0183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M739-0183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M739-0183 available by request