M739-0700 Screening compound: 4-{[1-(3,4-difluorobenzoyl)pyrrolidin-2-yl]methoxy}-N-(propan-2-yl)benzamide

M739-0700 Screening compound: 4-{[1-(3,4-difluorobenzoyl)pyrrolidin-2-yl]methoxy}-N-(propan-2-yl)benzamide
M739-0700 Screening compound: 4-{[1-(3,4-difluorobenzoyl)pyrrolidin-2-yl]methoxy}-N-(propan-2-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M739-0700
4-{[1-(3,4-difluorobenzoyl)pyrrolidin-2-yl]methoxy}-N-(propan-2-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M739-0700

Molecular Formula

C22H24F2N2O3 (C22 H24 F2 N2 O3)

Compound Name

4-{[1-(3,4-difluorobenzoyl)pyrrolidin-2-yl]methoxy}-N-(propan-2-yl)benzamide

IUPAC name

4-{[1-(34-difluorobenzoyl)pyrrolidin-2-yl]methoxy}-N-(propan-2-yl)benzamide

SMILES

CC(C)NC(c(cc1)ccc1OCC(CCC1)N1C(c(cc1)cc(F)c1F)=O)=O

InChI

InChI=1S/C22H24F2N2O3/c1-14(2)25-21(27)15-5-8-18(9-6-15)29-13-17-4-3-11-26(17)22(28)16-7-10-19(23)20(24)12-16/h5-10,12,14,17H,3-4,11,13H2,1-2H3,(H,25,27)/t17-/m1/s1

InChI Key

GKFIGIJGWKOTJL-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD27552441

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

402.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.419

Distribution Coefficient, logD

3.419

Water Solubility, LogSw

-3.70

Polar Surface Area

47.786

Acid Dissociation Constant (pKa)

14.33

Base Dissociation Constant (pKb)

-1.24

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

M739-0700 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with M739-0700 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M739-0700?
Check Price and Availability of M739-0700, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M739-0700 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M739-0700
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M739-0700
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M739-0700 available by request