M743-0038 Screening compound: 1-(3,4-difluorobenzoyl)-3-{[3-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

M743-0038 Screening compound: 1-(3,4-difluorobenzoyl)-3-{[3-(piperidine-1-carbonyl)phenoxy]methyl}piperidine
M743-0038 Screening compound: 1-(3,4-difluorobenzoyl)-3-{[3-(piperidine-1-carbonyl)phenoxy]methyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M743-0038
1-(3,4-difluorobenzoyl)-3-{[3-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M743-0038

Molecular Formula

C25H28F2N2O3 (C25 H28 F2 N2 O3)

Compound Name

1-(3,4-difluorobenzoyl)-3-{[3-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

IUPAC name

1-(34-difluorobenzoyl)-3-{[3-(piperidine-1-carbonyl)phenoxy]methyl}piperidine

SMILES

O=C(c1cccc(OCC(CCC2)CN2C(c(cc2)cc(F)c2F)=O)c1)N1CCCCC1

InChI

InChI=1S/C25H28F2N2O3/c26-22-10-9-20(15-23(22)27)25(31)29-13-5-6-18(16-29)17-32-21-8-4-7-19(14-21)24(30)28-11-2-1-3-12-28/h4,7-10,14-15,18H,1-3,5-6,11-13,16-17H2/t18-/m0/s1

InChI Key

UUXGRSYMMZMIPQ-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27552761

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.904

Distribution Coefficient, logD

3.904

Water Solubility, LogSw

-4.25

Polar Surface Area

40.696

Acid Dissociation Constant (pKa)

25.04

Base Dissociation Constant (pKb)

-1.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

M743-0038 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M743-0038 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M743-0038?
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What is the minimum amount of M743-0038 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M743-0038
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M743-0038
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M743-0038 available by request