M743-0199 Screening compound: 1-(3,4-difluorobenzoyl)-3-{[3-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

M743-0199 Screening compound: 1-(3,4-difluorobenzoyl)-3-{[3-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine
M743-0199 Screening compound: 1-(3,4-difluorobenzoyl)-3-{[3-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M743-0199
1-(3,4-difluorobenzoyl)-3-{[3-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M743-0199

Molecular Formula

C24H26F2N2O3 (C24 H26 F2 N2 O3)

Compound Name

1-(3,4-difluorobenzoyl)-3-{[3-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

IUPAC name

1-(34-difluorobenzoyl)-3-{[3-(pyrrolidine-1-carbonyl)phenoxy]methyl}piperidine

SMILES

O=C(c1cccc(OCC(CCC2)CN2C(c(cc2)cc(F)c2F)=O)c1)N1CCCC1

InChI

InChI=1S/C24H26F2N2O3/c25-21-9-8-19(14-22(21)26)24(30)28-12-4-5-17(15-28)16-31-20-7-3-6-18(13-20)23(29)27-10-1-2-11-27/h3,6-9,13-14,17H,1-2,4-5,10-12,15-16H2/t17-/m0/s1

InChI Key

CTQYTJUTKAYKGF-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27552810

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.616

Distribution Coefficient, logD

3.616

Water Solubility, LogSw

-3.92

Polar Surface Area

41.062

Acid Dissociation Constant (pKa)

25.04

Base Dissociation Constant (pKb)

-3.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

M743-0199 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M743-0199 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M743-0199?
Check Price and Availability of M743-0199, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M743-0199 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M743-0199
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M743-0199
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M743-0199 available by request