M743-0511 Screening compound: N-cyclopropyl-3-{[1-(thiophene-2-carbonyl)piperidin-3-yl]methoxy}benzamide

M743-0511 Screening compound: N-cyclopropyl-3-{[1-(thiophene-2-carbonyl)piperidin-3-yl]methoxy}benzamide
M743-0511 Screening compound: N-cyclopropyl-3-{[1-(thiophene-2-carbonyl)piperidin-3-yl]methoxy}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M743-0511
N-cyclopropyl-3-{[1-(thiophene-2-carbonyl)piperidin-3-yl]methoxy}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M743-0511

Molecular Formula

C21H24N2O3S (C21 H24 N2 O3 S)

Compound Name

N-cyclopropyl-3-{[1-(thiophene-2-carbonyl)piperidin-3-yl]methoxy}benzamide

IUPAC name

N-cyclopropyl-3-{[1-(thiophene-2-carbonyl)piperidin-3-yl]methoxy}benzamide

SMILES

O=C(c1cccs1)N1CC(COc2cc(C(NC3CC3)=O)ccc2)CCC1

InChI

InChI=1S/C21H24N2O3S/c24-20(22-17-8-9-17)16-5-1-6-18(12-16)26-14-15-4-2-10-23(13-15)21(25)19-7-3-11-27-19/h1,3,5-7,11-12,15,17H,2,4,8-10,13-14H2,(H,22,24)/t15-/m0/s1

InChI Key

MVDPXHPFYKOYGD-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27552890

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.362

Distribution Coefficient, logD

3.362

Water Solubility, LogSw

-3.77

Polar Surface Area

49.536

Acid Dissociation Constant (pKa)

12.95

Base Dissociation Constant (pKb)

-0.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.90

M743-0511 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M743-0511 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M743-0511?
Check Price and Availability of M743-0511, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M743-0511 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M743-0511
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M743-0511
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M743-0511 available by request