M745-0503 Screening compound: 4-{[1-(2-chlorobenzoyl)piperidin-4-yl]methoxy}-N-cyclopropylbenzamide

M745-0503 Screening compound: 4-{[1-(2-chlorobenzoyl)piperidin-4-yl]methoxy}-N-cyclopropylbenzamide
M745-0503 Screening compound: 4-{[1-(2-chlorobenzoyl)piperidin-4-yl]methoxy}-N-cyclopropylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M745-0503
4-{[1-(2-chlorobenzoyl)piperidin-4-yl]methoxy}-N-cyclopropylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M745-0503

Molecular Formula

C23H25ClN2O3 (C23 H25 ClN2 O3)

Compound Name

4-{[1-(2-chlorobenzoyl)piperidin-4-yl]methoxy}-N-cyclopropylbenzamide

IUPAC name

4-{[1-(2-chlorobenzoyl)piperidin-4-yl]methoxy}-N-cyclopropylbenzamide

SMILES

O=C(c(cc1)ccc1OCC(CC1)CCN1C(c(cccc1)c1Cl)=O)NC1CC1

InChI

InChI=1S/C23H25ClN2O3/c24-21-4-2-1-3-20(21)23(28)26-13-11-16(12-14-26)15-29-19-9-5-17(6-10-19)22(27)25-18-7-8-18/h1-6,9-10,16,18H,7-8,11-15H2,(H,25,27)

InChI Key

RAWSVKONUKACIL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27553111

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.92

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.593

Distribution Coefficient, logD

3.593

Water Solubility, LogSw

-4.10

Polar Surface Area

48.584

Acid Dissociation Constant (pKa)

12.64

Base Dissociation Constant (pKb)

-2.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

M745-0503 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with M745-0503 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M745-0503?
Check Price and Availability of M745-0503, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M745-0503 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M745-0503
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M745-0503
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M745-0503 available by request