M747-1024 Screening compound: 2-[4-(2-phenoxyethyl)piperidine-1-carbonyl]-1H-indole

M747-1024 Screening compound: 2-[4-(2-phenoxyethyl)piperidine-1-carbonyl]-1H-indole
M747-1024 Screening compound: 2-[4-(2-phenoxyethyl)piperidine-1-carbonyl]-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound M747-1024
2-[4-(2-phenoxyethyl)piperidine-1-carbonyl]-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M747-1024

Molecular Formula

C22H24N2O2 (C22 H24 N2 O2)

Compound Name

2-[4-(2-phenoxyethyl)piperidine-1-carbonyl]-1H-indole

IUPAC name

2-[4-(2-phenoxyethyl)piperidine-1-carbonyl]-1H-indole

SMILES

O=C(c1cc(cccc2)c2[nH]1)N1CCC(CCOc2ccccc2)CC1

InChI

InChI=1S/C22H24N2O2/c25-22(21-16-18-6-4-5-9-20(18)23-21)24-13-10-17(11-14-24)12-15-26-19-7-2-1-3-8-19/h1-9,16-17,23H,10-15H2

InChI Key

QIKRBNYQKWORRN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29019321

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

348.44

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.086

Distribution Coefficient, logD

5.086

Water Solubility, LogSw

-5.80

Polar Surface Area

33.382

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

M747-1024 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Structure:
  • Cyclic compounds
  • Mimetics
  • Mimetics
  • Cyclic compounds
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with M747-1024 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M747-1024?
Check Price and Availability of M747-1024, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M747-1024 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M747-1024
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M747-1024
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M747-1024 available by request