M754-1192 Screening compound: 2-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-1-(furan-2-carbonyl)piperidine

M754-1192 Screening compound: 2-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-1-(furan-2-carbonyl)piperidine
M754-1192 Screening compound: 2-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-1-(furan-2-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound M754-1192
2-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-1-(furan-2-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M754-1192

Molecular Formula

C15H18N4O2 (C15 H18 N4 O2)

Compound Name

2-(5-cyclopropyl-4H-1,2,4-triazol-3-yl)-1-(furan-2-carbonyl)piperidine

IUPAC name

2-(5-cyclopropyl-4H-124-triazol-3-yl)-1-(furan-2-carbonyl)piperidine

SMILES

O=C(c1ccco1)N(CCCC1)C1c1nnc(C2CC2)[nH]1

InChI

InChI=1S/C15H18N4O2/c20-15(12-5-3-9-21-12)19-8-2-1-4-11(19)14-16-13(17-18-14)10-6-7-10/h3,5,9-11H,1-2,4,6-8H2,(H,16,17,18)/t11-/m0/s1

InChI Key

PRCCGIGONWYXCY-NSHDSACASA-N

MDL Number (MFCD)

MFCD30462110

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

286.33

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.373

Distribution Coefficient, logD

1.371

Water Solubility, LogSw

-1.76

Polar Surface Area

59.196

Acid Dissociation Constant (pKa)

8.15

Base Dissociation Constant (pKb)

2.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

53.33

M754-1192 in Drug Discovery

Included in Screening Libraries

3D-Fragment Library (4274 compounds)

CNS MPO Library (28609 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with M754-1192 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M754-1192?
Check Price and Availability of M754-1192, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M754-1192 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M754-1192
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M754-1192
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M754-1192 available by request