M754-1500 Screening compound: 4-[5-(piperidin-2-yl)-4H-1,2,4-triazol-3-yl]pyridine

M754-1500 Screening compound: 4-[5-(piperidin-2-yl)-4H-1,2,4-triazol-3-yl]pyridine
M754-1500 Screening compound: 4-[5-(piperidin-2-yl)-4H-1,2,4-triazol-3-yl]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound M754-1500
4-[5-(piperidin-2-yl)-4H-1,2,4-triazol-3-yl]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M754-1500

Molecular Formula

C12H15N5 (C12 H15 N5)

Compound Name

4-[5-(piperidin-2-yl)-4H-1,2,4-triazol-3-yl]pyridine

IUPAC name

4-[5-(piperidin-2-yl)-4H-124-triazol-3-yl]pyridine

SMILES

C1CC(c2nnc(-c3ccncc3)[nH]2)NCC1

InChI

InChI=1S/C12H15N5/c1-2-6-14-10(3-1)12-15-11(16-17-12)9-4-7-13-8-5-9/h4-5,7-8,10,14H,1-3,6H2,(H,15,16,17)/t10-/m0/s1

InChI Key

RPYAPCTURZSAHA-JTQLQIEISA-N

MDL Number (MFCD)

MFCD22093995

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

229.28

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

0.183

Distribution Coefficient, logD

0.027

Water Solubility, LogSw

-0.66

Polar Surface Area

55.485

Acid Dissociation Constant (pKa)

3.62

Base Dissociation Constant (pKb)

6.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.67

M754-1500 in Drug Discovery

Included in Screening Libraries

3D-Fragment Library (4274 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Fragments
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with M754-1500 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M754-1500?
Check Price and Availability of M754-1500, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M754-1500 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M754-1500
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M754-1500
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M754-1500 available by request