M758-2043 Screening compound: N-(cyclopropylmethyl)-1-(2,5-difluorobenzoyl)-N-[(pyridin-4-yl)methyl]azetidin-3-amine

M758-2043 Screening compound: N-(cyclopropylmethyl)-1-(2,5-difluorobenzoyl)-N-[(pyridin-4-yl)methyl]azetidin-3-amine
M758-2043 Screening compound: N-(cyclopropylmethyl)-1-(2,5-difluorobenzoyl)-N-[(pyridin-4-yl)methyl]azetidin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound M758-2043
N-(cyclopropylmethyl)-1-(2,5-difluorobenzoyl)-N-[(pyridin-4-yl)methyl]azetidin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M758-2043

Molecular Formula

C20H21F2N3O (C20 H21 F2 N3 O)

Compound Name

N-(cyclopropylmethyl)-1-(2,5-difluorobenzoyl)-N-[(pyridin-4-yl)methyl]azetidin-3-amine

IUPAC name

N-(cyclopropylmethyl)-1-(25-difluorobenzoyl)-N-[(pyridin-4-yl)methyl]azetidin-3-amine

SMILES

O=C(c(cc(cc1)F)c1F)N(C1)CC1N(CC1CC1)Cc1ccncc1

InChI

InChI=1S/C20H21F2N3O/c21-16-3-4-19(22)18(9-16)20(26)25-12-17(13-25)24(10-14-1-2-14)11-15-5-7-23-8-6-15/h3-9,14,17H,1-2,10-13H2

InChI Key

IAHADOQWDCWHHT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31979187

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

2.475

Distribution Coefficient, logD

1.891

Water Solubility, LogSw

-2.66

Polar Surface Area

29.421

Acid Dissociation Constant (pKa)

25.63

Base Dissociation Constant (pKb)

7.85

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

M758-2043 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS BBB Library (22607 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M758-2043 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M758-2043?
Check Price and Availability of M758-2043, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M758-2043 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M758-2043
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M758-2043
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M758-2043 available by request