M759-2848 Screening compound: 3-(4-methoxyphenyl)-1-{3-[(2-methylpropyl)[(pyridin-3-yl)methyl]amino]azetidin-1-yl}propan-1-one

M759-2848 Screening compound: 3-(4-methoxyphenyl)-1-{3-[(2-methylpropyl)[(pyridin-3-yl)methyl]amino]azetidin-1-yl}propan-1-one
M759-2848 Screening compound: 3-(4-methoxyphenyl)-1-{3-[(2-methylpropyl)[(pyridin-3-yl)methyl]amino]azetidin-1-yl}propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M759-2848
3-(4-methoxyphenyl)-1-{3-[(2-methylpropyl)[(pyridin-3-yl)methyl]amino]azetidin-1-yl}propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M759-2848

Molecular Formula

C23H31N3O2 (C23 H31 N3 O2)

Compound Name

3-(4-methoxyphenyl)-1-{3-[(2-methylpropyl)[(pyridin-3-yl)methyl]amino]azetidin-1-yl}propan-1-one

IUPAC name

3-(4-methoxyphenyl)-1-{3-[(2-methylpropyl)[(pyridin-3-yl)methyl]amino]azetidin-1-yl}propan-1-one

SMILES

CC(C)CN(Cc1cnccc1)C(C1)CN1C(CCc(cc1)ccc1OC)=O

InChI

InChI=1S/C23H31N3O2/c1-18(2)14-25(15-20-5-4-12-24-13-20)21-16-26(17-21)23(27)11-8-19-6-9-22(28-3)10-7-19/h4-7,9-10,12-13,18,21H,8,11,14-17H2,1-3H3

InChI Key

LHIWUKXYVBZAMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31975998

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.985

Distribution Coefficient, logD

2.706

Water Solubility, LogSw

-2.88

Polar Surface Area

36.275

Acid Dissociation Constant (pKa)

22.66

Base Dissociation Constant (pKb)

7.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.83

M759-2848 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS BBB Library (22607 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with M759-2848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M759-2848?
Check Price and Availability of M759-2848, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M759-2848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M759-2848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M759-2848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M759-2848 available by request