M777-0005 Screening compound: N~2~-(1-methyl-6-oxo-5-piperidino-1,6-dihydro-4-pyridazinyl)-2-thiophenecarboxamide

M777-0005 Screening compound: N~2~-(1-methyl-6-oxo-5-piperidino-1,6-dihydro-4-pyridazinyl)-2-thiophenecarboxamide
M777-0005 Screening compound: N~2~-(1-methyl-6-oxo-5-piperidino-1,6-dihydro-4-pyridazinyl)-2-thiophenecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M777-0005
N~2~-(1-methyl-6-oxo-5-piperidino-1,6-dihydro-4-pyridazinyl)-2-thiophenecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M777-0005

Molecular Formula

C15H18N4O2S (C15 H18 N4 O2 S)

Compound Name

N~2~-(1-methyl-6-oxo-5-piperidino-1,6-dihydro-4-pyridazinyl)-2-thiophenecarboxamide

IUPAC name

N-[1-methyl-6-oxo-5-(piperidin-1-yl)-16-dihydropyridazin-4-yl]thiophene-2-carboxamide

SMILES

CN(C1=O)N=CC(NC(c2cccs2)=O)=C1N1CCCCC1

InChI

InChI=1S/C15H18N4O2S/c1-18-15(21)13(19-7-3-2-4-8-19)11(10-16-18)17-14(20)12-6-5-9-22-12/h5-6,9-10H,2-4,7-8H2,1H3,(H,17,20)

InChI Key

YZIJRDZPMVTOTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27553683

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

318.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.659

Distribution Coefficient, logD

1.629

Water Solubility, LogSw

-2.27

Polar Surface Area

55.741

Acid Dissociation Constant (pKa)

8.73

Base Dissociation Constant (pKb)

4.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

M777-0005 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • GPCR
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M777-0005 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M777-0005?
Check Price and Availability of M777-0005, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M777-0005 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M777-0005
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M777-0005
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M777-0005 available by request