M777-0373 Screening compound: N-[1-ethyl-5-(morpholin-4-yl)-6-oxo-1,6-dihydropyridazin-4-yl]-2-methoxybenzamide

M777-0373 Screening compound: N-[1-ethyl-5-(morpholin-4-yl)-6-oxo-1,6-dihydropyridazin-4-yl]-2-methoxybenzamide
M777-0373 Screening compound: N-[1-ethyl-5-(morpholin-4-yl)-6-oxo-1,6-dihydropyridazin-4-yl]-2-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M777-0373
N-[1-ethyl-5-(morpholin-4-yl)-6-oxo-1,6-dihydropyridazin-4-yl]-2-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M777-0373

Molecular Formula

C18H22N4O4 (C18 H22 N4 O4)

Compound Name

N-[1-ethyl-5-(morpholin-4-yl)-6-oxo-1,6-dihydropyridazin-4-yl]-2-methoxybenzamide

IUPAC name

N-[1-ethyl-5-(morpholin-4-yl)-6-oxo-16-dihydropyridazin-4-yl]-2-methoxybenzamide

SMILES

CCN(C1=O)N=CC(NC(c(cccc2)c2OC)=O)=C1N1CCOCC1

InChI

InChI=1S/C18H22N4O4/c1-3-22-18(24)16(21-8-10-26-11-9-21)14(12-19-22)20-17(23)13-6-4-5-7-15(13)25-2/h4-7,12H,3,8-11H2,1-2H3,(H,20,23)

InChI Key

RLHRWTLFTATKTK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27553765

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.828

Distribution Coefficient, logD

-0.080

Water Solubility, LogSw

-2.47

Polar Surface Area

70.308

Acid Dissociation Constant (pKa)

6.55

Base Dissociation Constant (pKb)

3.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

M777-0373 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Proteases
  • Ion Channels

References: we are preparing a list of scientific research reports with M777-0373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M777-0373?
Check Price and Availability of M777-0373, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M777-0373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M777-0373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M777-0373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M777-0373 available by request