M916-0164 Screening compound: N-[4-(morpholin-4-yl)phenyl]-3-[(1,3,9-trimethyl-2,6-dioxo-2,3,6,9-tetrahydro-1H-purin-8-yl)sulfonyl]propanamide

M916-0164 Screening compound: N-[4-(morpholin-4-yl)phenyl]-3-[(1,3,9-trimethyl-2,6-dioxo-2,3,6,9-tetrahydro-1H-purin-8-yl)sulfonyl]propanamide
M916-0164 Screening compound: N-[4-(morpholin-4-yl)phenyl]-3-[(1,3,9-trimethyl-2,6-dioxo-2,3,6,9-tetrahydro-1H-purin-8-yl)sulfonyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M916-0164
N-[4-(morpholin-4-yl)phenyl]-3-[(1,3,9-trimethyl-2,6-dioxo-2,3,6,9-tetrahydro-1H-purin-8-yl)sulfonyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M916-0164

Molecular Formula

C21H26N6O6S (C21 H26 N6 O6 S)

Compound Name

N-[4-(morpholin-4-yl)phenyl]-3-[(1,3,9-trimethyl-2,6-dioxo-2,3,6,9-tetrahydro-1H-purin-8-yl)sulfonyl]propanamide

IUPAC name

N-[4-(morpholin-4-yl)phenyl]-3-[(139-trimethyl-26-dioxo-2369-tetrahydro-1H-purin-8-yl)sulfonyl]propanamide

SMILES

Cn1c(S(CCC(Nc(cc2)ccc2N2CCOCC2)=O)(=O)=O)nc(C(N2C)=O)c1N(C)C2=O

InChI

InChI=1S/C21H26N6O6S/c1-24-18-17(19(29)26(3)21(30)25(18)2)23-20(24)34(31,32)13-8-16(28)22-14-4-6-15(7-5-14)27-9-11-33-12-10-27/h4-7H,8-13H2,1-3H3,(H,22,28)

InChI Key

IFJZOERHMGEAOW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27556596

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.54

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

12

Partition Coefficient, logP

0.580

Distribution Coefficient, logD

0.579

Water Solubility, LogSw

-2.27

Polar Surface Area

107.958

Acid Dissociation Constant (pKa)

12.54

Base Dissociation Constant (pKb)

6.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

M916-0164 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleoside Mimetics Library (2197 compounds)

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Purine Based Nucleoside Mimetics Library (1131 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Cancer
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Mimetics
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with M916-0164 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M916-0164?
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What is the minimum amount of M916-0164 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M916-0164
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M916-0164
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M916-0164 available by request