M923-0949 Screening compound: 3-(2,6-difluorophenyl)-1-{3-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}urea

M923-0949 Screening compound: 3-(2,6-difluorophenyl)-1-{3-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}urea
M923-0949 Screening compound: 3-(2,6-difluorophenyl)-1-{3-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound M923-0949
3-(2,6-difluorophenyl)-1-{3-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M923-0949

Molecular Formula

C21H19F2N5O (C21 H19 F2 N5 O)

Compound Name

3-(2,6-difluorophenyl)-1-{3-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}urea

IUPAC name

3-(26-difluorophenyl)-1-{3-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}urea

SMILES

O=C(Nc1cc(-c(cc2)nnc2N2CCCC2)ccc1)Nc(c(F)ccc1)c1F

InChI

InChI=1S/C21H19F2N5O/c22-16-7-4-8-17(23)20(16)25-21(29)24-15-6-3-5-14(13-15)18-9-10-19(27-26-18)28-11-1-2-12-28/h3-10,13H,1-2,11-12H2,(H2,24,25,29)

InChI Key

NHMHUAROTWEHQN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29019592

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.805

Distribution Coefficient, logD

4.803

Water Solubility, LogSw

-4.82

Polar Surface Area

55.899

Acid Dissociation Constant (pKa)

9.94

Base Dissociation Constant (pKb)

6.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

M923-0949 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with M923-0949 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M923-0949?
Check Price and Availability of M923-0949, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M923-0949 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M923-0949
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M923-0949
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M923-0949 available by request