M976-0078 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-4-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

M976-0078 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-4-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one
M976-0078 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-4-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound M976-0078
1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-4-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M976-0078

Molecular Formula

C24H27N5O3 (C24 H27 N5 O3)

Compound Name

1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-4-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

IUPAC name

1-(1-acetyl-23-dihydro-1H-indol-5-yl)-4-[4-(pyridin-2-yl)piperazine-1-carbonyl]pyrrolidin-2-one

SMILES

CC(N(CC1)c(cc2)c1cc2N(CC(C1)C(N(CC2)CCN2c2ncccc2)=O)C1=O)=O

InChI

InChI=1S/C24H27N5O3/c1-17(30)28-9-7-18-14-20(5-6-21(18)28)29-16-19(15-23(29)31)24(32)27-12-10-26(11-13-27)22-4-2-3-8-25-22/h2-6,8,14,19H,7,9-13,15-16H2,1H3/t19-/m1/s1

InChI Key

OBYPUCCJSOSFKQ-LJQANCHMSA-N

MDL Number (MFCD)

MFCD27558218

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.424

Distribution Coefficient, logD

1.415

Water Solubility, LogSw

-1.82

Polar Surface Area

61.827

Acid Dissociation Constant (pKa)

13.27

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

M976-0078 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

GPCR Targeted Library (31838 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Epigenetics Focused Set (26518 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • GPCR
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with M976-0078 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M976-0078?
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What is the minimum amount of M976-0078 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M976-0078
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M976-0078
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M976-0078 available by request