M976-0125 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-N-(2-fluoro-5-methylphenyl)-5-oxopyrrolidine-3-carboxamide

M976-0125 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-N-(2-fluoro-5-methylphenyl)-5-oxopyrrolidine-3-carboxamide
M976-0125 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-N-(2-fluoro-5-methylphenyl)-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M976-0125
1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-N-(2-fluoro-5-methylphenyl)-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M976-0125

Molecular Formula

C22H22FN3O3 (C22 H22 FN3 O3)

Compound Name

1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-N-(2-fluoro-5-methylphenyl)-5-oxopyrrolidine-3-carboxamide

IUPAC name

1-(1-acetyl-23-dihydro-1H-indol-5-yl)-N-(2-fluoro-5-methylphenyl)-5-oxopyrrolidine-3-carboxamide

SMILES

CC(N(CC1)c(cc2)c1cc2N(CC(C1)C(Nc(cc(C)cc2)c2F)=O)C1=O)=O

InChI

InChI=1S/C22H22FN3O3/c1-13-3-5-18(23)19(9-13)24-22(29)16-11-21(28)26(12-16)17-4-6-20-15(10-17)7-8-25(20)14(2)27/h3-6,9-10,16H,7-8,11-12H2,1-2H3,(H,24,29)/t16-/m0/s1

InChI Key

ODPGIXADSOLGDS-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27558255

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.158

Distribution Coefficient, logD

2.156

Water Solubility, LogSw

-2.85

Polar Surface Area

55.800

Acid Dissociation Constant (pKa)

9.69

Base Dissociation Constant (pKb)

3.24

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

M976-0125 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with M976-0125 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M976-0125?
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What is the minimum amount of M976-0125 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M976-0125
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M976-0125
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M976-0125 available by request