M976-0172 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-5-oxo-N~3~-[1-(2-pyridyl)ethyl]-3-pyrrolidinecarboxamide

M976-0172 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-5-oxo-N~3~-[1-(2-pyridyl)ethyl]-3-pyrrolidinecarboxamide
M976-0172 Screening compound: 1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-5-oxo-N~3~-[1-(2-pyridyl)ethyl]-3-pyrrolidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M976-0172
1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-5-oxo-N~3~-[1-(2-pyridyl)ethyl]-3-pyrrolidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M976-0172

Molecular Formula

C22H24N4O3 (C22 H24 N4 O3)

Compound Name

1-(1-acetyl-2,3-dihydro-1H-indol-5-yl)-5-oxo-N~3~-[1-(2-pyridyl)ethyl]-3-pyrrolidinecarboxamide

IUPAC name

n/a

SMILES

CC(c1ncccc1)NC(C(CC1=O)CN1c(cc1)cc(CC2)c1N2C(C)=O)=O

InChI

InChI=1S/C22H24N4O3/c1-14(19-5-3-4-9-23-19)24-22(29)17-12-21(28)26(13-17)18-6-7-20-16(11-18)8-10-25(20)15(2)27/h3-7,9,11,14,17H,8,10,12-13H2,1-2H3,(H,24,29)

InChI Key

BOTAQYPTSVDPPS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27558280

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.501

Distribution Coefficient, logD

0.501

Water Solubility, LogSw

-1.79

Polar Surface Area

66.031

Acid Dissociation Constant (pKa)

11.66

Base Dissociation Constant (pKb)

3.82

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

36.40

M976-0172 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • Proteases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with M976-0172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M976-0172?
Check Price and Availability of M976-0172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of M976-0172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M976-0172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M976-0172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M976-0172 available by request