M976-0487 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

M976-0487 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
M976-0487 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M976-0487
1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M976-0487

Molecular Formula

C24H25N3O4 (C24 H25 N3 O4)

Compound Name

1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

IUPAC name

1-(1-cyclopropanecarbonyl-23-dihydro-1H-indol-5-yl)-N-(3-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

SMILES

COc1cccc(NC(C(CC2=O)CN2c(cc2)cc(CC3)c2N3C(C2CC2)=O)=O)c1

InChI

InChI=1S/C24H25N3O4/c1-31-20-4-2-3-18(13-20)25-23(29)17-12-22(28)27(14-17)19-7-8-21-16(11-19)9-10-26(21)24(30)15-5-6-15/h2-4,7-8,11,13,15,17H,5-6,9-10,12,14H2,1H3,(H,25,29)/t17-/m1/s1

InChI Key

KVZHYVAOIIQPHI-QGZVFWFLSA-N

MDL Number (MFCD)

MFCD27558361

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.451

Distribution Coefficient, logD

2.450

Water Solubility, LogSw

-3.00

Polar Surface Area

63.825

Acid Dissociation Constant (pKa)

10.41

Base Dissociation Constant (pKb)

4.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

M976-0487 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with M976-0487 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M976-0487?
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What is the minimum amount of M976-0487 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M976-0487
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M976-0487
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M976-0487 available by request