M976-0566 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-[(2,4-difluorophenyl)methyl]-5-oxopyrrolidine-3-carboxamide

M976-0566 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-[(2,4-difluorophenyl)methyl]-5-oxopyrrolidine-3-carboxamide
M976-0566 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-[(2,4-difluorophenyl)methyl]-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M976-0566
1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-[(2,4-difluorophenyl)methyl]-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M976-0566

Molecular Formula

C24H23F2N3O3 (C24 H23 F2 N3 O3)

Compound Name

1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-[(2,4-difluorophenyl)methyl]-5-oxopyrrolidine-3-carboxamide

IUPAC name

1-(1-cyclopropanecarbonyl-23-dihydro-1H-indol-5-yl)-N-[(24-difluorophenyl)methyl]-5-oxopyrrolidine-3-carboxamide

SMILES

O=C(C1CC1)N(CC1)c(cc2)c1cc2N(CC(C1)C(NCc(ccc(F)c2)c2F)=O)C1=O

InChI

InChI=1S/C24H23F2N3O3/c25-18-4-3-16(20(26)11-18)12-27-23(31)17-10-22(30)29(13-17)19-5-6-21-15(9-19)7-8-28(21)24(32)14-1-2-14/h3-6,9,11,14,17H,1-2,7-8,10,12-13H2,(H,27,31)/t17-/m0/s1

InChI Key

GLEZUVDUSDLGGF-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27558394

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.487

Distribution Coefficient, logD

2.487

Water Solubility, LogSw

-2.91

Polar Surface Area

57.604

Acid Dissociation Constant (pKa)

11.46

Base Dissociation Constant (pKb)

4.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

M976-0566 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • GPCR

References: we are preparing a list of scientific research reports with M976-0566 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M976-0566?
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What is the minimum amount of M976-0566 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M976-0566
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M976-0566
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M976-0566 available by request