M976-0574 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

M976-0574 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide
M976-0574 Screening compound: 1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound M976-0574
1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

M976-0574

Molecular Formula

C24H24FN3O4 (C24 H24 FN3 O4)

Compound Name

1-(1-cyclopropanecarbonyl-2,3-dihydro-1H-indol-5-yl)-N-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

IUPAC name

1-(1-cyclopropanecarbonyl-23-dihydro-1H-indol-5-yl)-N-(3-fluoro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxamide

SMILES

COc(ccc(NC(C(CC1=O)CN1c(cc1)cc(CC2)c1N2C(C1CC1)=O)=O)c1)c1F

InChI

InChI=1S/C24H24FN3O4/c1-32-21-7-4-17(12-19(21)25)26-23(30)16-11-22(29)28(13-16)18-5-6-20-15(10-18)8-9-27(20)24(31)14-2-3-14/h4-7,10,12,14,16H,2-3,8-9,11,13H2,1H3,(H,26,30)/t16-/m0/s1

InChI Key

ODYHMAWXPRVVCP-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27558399

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.475

Distribution Coefficient, logD

2.468

Water Solubility, LogSw

-3.09

Polar Surface Area

63.912

Acid Dissociation Constant (pKa)

9.19

Base Dissociation Constant (pKb)

4.52

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

M976-0574 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

KRAS-Targeted Library (16000 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics

References: we are preparing a list of scientific research reports with M976-0574 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound M976-0574?
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What is the minimum amount of M976-0574 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for M976-0574
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for M976-0574
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of M976-0574 available by request