N011-0459 Screening compound: 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline

N011-0459 Screening compound: 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
N011-0459 Screening compound: 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound N011-0459
6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

N011-0459

Molecular Formula

C12H17NO2 (C12 H17 NO2)

Compound Name

6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline

IUPAC name

67-dimethoxy-1-methyl-1234-tetrahydroisoquinoline

SMILES

CC(c1c2)NCCc1cc(OC)c2OC

InChI

InChI=1S/C12H17NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h6-8,13H,4-5H2,1-3H3/t8-/m0/s1

InChI Key

HMYJLVDKPJHJCF-QMMMGPOBSA-N

MDL Number (MFCD)

MFCD00694774

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

207.27

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

1.000

Distribution Coefficient, logD

-2.243

Water Solubility, LogSw

-1.38

Polar Surface Area

27.189

Acid Dissociation Constant (pKa)

25.65

Base Dissociation Constant (pKb)

10.64

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

N011-0459 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

CNS BBB Library (22607 compounds)

CNS MPO Library (28609 compounds)

CNS Targets (44014 compounds)

Dark Chemical Matter Library (18430 compounds)

Fragments Library (11262 compounds)

Targeted Diversity Library (40567 compounds)

Ion Channels Focused Library (26372 compounds)

Natural Compounds Library (353 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Nervous system
  • Nervous system
  • Nervous system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
Structure:
  • Pool
  • Fragments
Targets:
  • Ion Channels
  • Phosphatases

References: we are preparing a list of scientific research reports with N011-0459 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound N011-0459?
Check Price and Availability of N011-0459, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of N011-0459 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for N011-0459
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for N011-0459
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of N011-0459 available by request