N081-0782 Screening compound: 3-{[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl}-2-[(4-methylphenyl)methyl]propanoic acid

N081-0782 Screening compound: 3-{[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl}-2-[(4-methylphenyl)methyl]propanoic acid
N081-0782 Screening compound: 3-{[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl}-2-[(4-methylphenyl)methyl]propanoic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound N081-0782
3-{[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl}-2-[(4-methylphenyl)methyl]propanoic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

N081-0782

Molecular Formula

C22H27NO5 (C22 H27 NO5)

Compound Name

3-{[2-(3,4-dimethoxyphenyl)ethyl]carbamoyl}-2-[(4-methylphenyl)methyl]propanoic acid

IUPAC name

3-{[2-(34-dimethoxyphenyl)ethyl]carbamoyl}-2-[(4-methylphenyl)methyl]propanoic acid

SMILES

Cc1ccc(CC(CC(NCCc(cc2)cc(OC)c2OC)=O)C(O)=O)cc1

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.229

Distribution Coefficient, logD

-0.425

Water Solubility, LogSw

-2.68

Polar Surface Area

67.949

Acid Dissociation Constant (pKa)

4.75

Base Dissociation Constant (pKb)

-0.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

36.40

N081-0782 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Anti-Aging Library (44940 compounds)

Dark Chemical Matter Library (18430 compounds)

Eccentric PPI Library (11937 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

SH2 PTB Focused Library (6188 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Pool
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • Epigenetic
  • PPI modulators
  • PPI modulators
  • Receptor's ligands
Targets:
  • Nuclear receptors
  • Proteases
  • Phosphatases

References: we are preparing a list of scientific research reports with N081-0782 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound N081-0782?
Check Price and Availability of N081-0782, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of N081-0782 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for N081-0782
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for N081-0782
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of N081-0782 available by request