P018-1909 Screening compound: 5-chloro-N-{[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl}-2-fluorobenzamide

P018-1909 Screening compound: 5-chloro-N-{[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl}-2-fluorobenzamide
P018-1909 Screening compound: 5-chloro-N-{[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl}-2-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P018-1909
5-chloro-N-{[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl}-2-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P018-1909

Molecular Formula

C17H13ClFN3O2S (C17 H13 ClFN3 O2 S)

Compound Name

5-chloro-N-{[5-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)thiophen-2-yl]methyl}-2-fluorobenzamide

IUPAC name

5-chloro-N-{[5-(3-cyclopropyl-124-oxadiazol-5-yl)thiophen-2-yl]methyl}-2-fluorobenzamide

SMILES

O=C(c(cc(cc1)Cl)c1F)NCc1ccc(-c2nc(C3CC3)no2)s1

InChI

InChI=1S/C17H13ClFN3O2S/c18-10-3-5-13(19)12(7-10)16(23)20-8-11-4-6-14(25-11)17-21-15(22-24-17)9-1-2-9/h3-7,9H,1-2,8H2,(H,20,23)

InChI Key

CQFWVFRTYOYFLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27558790

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.83

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.139

Distribution Coefficient, logD

5.138

Water Solubility, LogSw

-5.48

Polar Surface Area

57.599

Acid Dissociation Constant (pKa)

10.78

Base Dissociation Constant (pKb)

0.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

P018-1909 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with P018-1909 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P018-1909?
Check Price and Availability of P018-1909, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P018-1909 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P018-1909
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P018-1909
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P018-1909 available by request