P019-1378 Screening compound: N-(4-fluoro-2-methylphenyl)-2-({3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}sulfanyl)acetamide

P019-1378 Screening compound: N-(4-fluoro-2-methylphenyl)-2-({3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}sulfanyl)acetamide
P019-1378 Screening compound: N-(4-fluoro-2-methylphenyl)-2-({3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P019-1378
N-(4-fluoro-2-methylphenyl)-2-({3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P019-1378

Molecular Formula

C23H19FN4O2S (C23 H19 FN4 O2 S)

Compound Name

N-(4-fluoro-2-methylphenyl)-2-({3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}sulfanyl)acetamide

IUPAC name

N-(4-fluoro-2-methylphenyl)-2-({3-[3-(4-methylphenyl)-124-oxadiazol-5-yl]pyridin-2-yl}sulfanyl)acetamide

SMILES

Cc(cc1)ccc1-c1noc(-c2cccnc2SCC(Nc(cc2)c(C)cc2F)=O)n1

InChI

InChI=1S/C23H19FN4O2S/c1-14-5-7-16(8-6-14)21-27-22(30-28-21)18-4-3-11-25-23(18)31-13-20(29)26-19-10-9-17(24)12-15(19)2/h3-12H,13H2,1-2H3,(H,26,29)

InChI Key

PLPYVFJAXNCLIE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27558815

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.008

Distribution Coefficient, logD

5.008

Water Solubility, LogSw

-4.56

Polar Surface Area

63.003

Acid Dissociation Constant (pKa)

10.80

Base Dissociation Constant (pKb)

2.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

P019-1378 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P019-1378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P019-1378?
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What is the minimum amount of P019-1378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P019-1378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P019-1378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P019-1378 available by request