P033-0643 Screening compound: 1-[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridine-3-carbonyl]-4-(3-methoxyphenyl)piperazine

P033-0643 Screening compound: 1-[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridine-3-carbonyl]-4-(3-methoxyphenyl)piperazine
P033-0643 Screening compound: 1-[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridine-3-carbonyl]-4-(3-methoxyphenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound P033-0643
1-[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridine-3-carbonyl]-4-(3-methoxyphenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P033-0643

Molecular Formula

C22H25N5O2 (C22 H25 N5 O2)

Compound Name

1-[6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridine-3-carbonyl]-4-(3-methoxyphenyl)piperazine

IUPAC name

1-[6-(35-dimethyl-1H-pyrazol-1-yl)pyridine-3-carbonyl]-4-(3-methoxyphenyl)piperazine

SMILES

Cc1cc(C)nn1-c(cc1)ncc1C(N(CC1)CCN1c1cc(OC)ccc1)=O

InChI

InChI=1S/C22H25N5O2/c1-16-13-17(2)27(24-16)21-8-7-18(15-23-21)22(28)26-11-9-25(10-12-26)19-5-4-6-20(14-19)29-3/h4-8,13-15H,9-12H2,1-3H3

InChI Key

LREWVYYOESVSRY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27559465

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

391.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.654

Distribution Coefficient, logD

2.653

Water Solubility, LogSw

-2.65

Polar Surface Area

50.163

Acid Dissociation Constant (pKa)

27.97

Base Dissociation Constant (pKb)

4.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.82

P033-0643 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P033-0643 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P033-0643?
Check Price and Availability of P033-0643, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P033-0643 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P033-0643
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P033-0643
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P033-0643 available by request