P035-1489 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-1-(5-cyclopropaneamidopyridin-2-yl)-1H-imidazole-4-carboxamide

P035-1489 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-1-(5-cyclopropaneamidopyridin-2-yl)-1H-imidazole-4-carboxamide
P035-1489 Screening compound: N-[(2-chloro-4-fluorophenyl)methyl]-1-(5-cyclopropaneamidopyridin-2-yl)-1H-imidazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P035-1489
N-[(2-chloro-4-fluorophenyl)methyl]-1-(5-cyclopropaneamidopyridin-2-yl)-1H-imidazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P035-1489

Molecular Formula

C20H17ClFN5O2 (C20 H17 ClFN5 O2)

Compound Name

N-[(2-chloro-4-fluorophenyl)methyl]-1-(5-cyclopropaneamidopyridin-2-yl)-1H-imidazole-4-carboxamide

IUPAC name

N-[(2-chloro-4-fluorophenyl)methyl]-1-(5-cyclopropaneamidopyridin-2-yl)-1H-imidazole-4-carboxamide

SMILES

O=C(C1CC1)Nc(cc1)cnc1-n1cnc(C(NCc(ccc(F)c2)c2Cl)=O)c1

InChI

InChI=1S/C20H17ClFN5O2/c21-16-7-14(22)4-3-13(16)8-24-20(29)17-10-27(11-25-17)18-6-5-15(9-23-18)26-19(28)12-1-2-12/h3-7,9-12H,1-2,8H2,(H,24,29)(H,26,28)

InChI Key

YKCQGEJRNDSIQA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27559694

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.84

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.886

Distribution Coefficient, logD

3.886

Water Solubility, LogSw

-4.23

Polar Surface Area

69.105

Acid Dissociation Constant (pKa)

12.09

Base Dissociation Constant (pKb)

4.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

P035-1489 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with P035-1489 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P035-1489?
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What is the minimum amount of P035-1489 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P035-1489
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P035-1489
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P035-1489 available by request