P038-4231 Screening compound: methyl 3-{3-methyl-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-amido}benzoate

P038-4231 Screening compound: methyl 3-{3-methyl-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-amido}benzoate
P038-4231 Screening compound: methyl 3-{3-methyl-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-amido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound P038-4231
methyl 3-{3-methyl-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-amido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P038-4231

Molecular Formula

C23H18N4O5 (C23 H18 N4 O5)

Compound Name

methyl 3-{3-methyl-2,4-dioxo-1-phenyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-amido}benzoate

IUPAC name

methyl 3-{3-methyl-24-dioxo-1-phenyl-1H2H3H4H-pyrido[23-d]pyrimidine-6-amido}benzoate

SMILES

CN(C(c1cc(C(Nc2cc(C(OC)=O)ccc2)=O)cnc1N1c2ccccc2)=O)C1=O

InChI

InChI=1S/C23H18N4O5/c1-26-21(29)18-12-15(20(28)25-16-8-6-7-14(11-16)22(30)32-2)13-24-19(18)27(23(26)31)17-9-4-3-5-10-17/h3-13H,1-2H3,(H,25,28)

InChI Key

BBMGQUXQGCZWTN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27559735

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.42

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.252

Distribution Coefficient, logD

3.245

Water Solubility, LogSw

-3.66

Polar Surface Area

85.378

Acid Dissociation Constant (pKa)

9.18

Base Dissociation Constant (pKb)

0.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

P038-4231 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

SH2 Library (10483 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Endocrine
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with P038-4231 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P038-4231?
Check Price and Availability of P038-4231, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P038-4231 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P038-4231
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P038-4231
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P038-4231 available by request