P038-4729 Screening compound: N-(3-fluoro-4-methoxyphenyl)-3-methyl-1-(4-methylphenyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

P038-4729 Screening compound: N-(3-fluoro-4-methoxyphenyl)-3-methyl-1-(4-methylphenyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide
P038-4729 Screening compound: N-(3-fluoro-4-methoxyphenyl)-3-methyl-1-(4-methylphenyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P038-4729
N-(3-fluoro-4-methoxyphenyl)-3-methyl-1-(4-methylphenyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P038-4729

Molecular Formula

C23H19FN4O4 (C23 H19 FN4 O4)

Compound Name

N-(3-fluoro-4-methoxyphenyl)-3-methyl-1-(4-methylphenyl)-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(3-fluoro-4-methoxyphenyl)-3-methyl-1-(4-methylphenyl)-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidine-6-carboxamide

SMILES

Cc(cc1)ccc1N(c(c(C(N1C)=O)c2)ncc2C(Nc(cc2)cc(F)c2OC)=O)C1=O

InChI

InChI=1S/C23H19FN4O4/c1-13-4-7-16(8-5-13)28-20-17(22(30)27(2)23(28)31)10-14(12-25-20)21(29)26-15-6-9-19(32-3)18(24)11-15/h4-12H,1-3H3,(H,26,29)

InChI Key

ICCPTROLBDKUAT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27559797

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.617

Distribution Coefficient, logD

3.383

Water Solubility, LogSw

-3.78

Polar Surface Area

71.835

Acid Dissociation Constant (pKa)

7.55

Base Dissociation Constant (pKb)

0.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

P038-4729 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with P038-4729 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P038-4729?
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What is the minimum amount of P038-4729 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P038-4729
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P038-4729
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P038-4729 available by request