P038-4891 Screening compound: N-[(2-fluorophenyl)methyl]-1-(4-methoxyphenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

P038-4891 Screening compound: N-[(2-fluorophenyl)methyl]-1-(4-methoxyphenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide
P038-4891 Screening compound: N-[(2-fluorophenyl)methyl]-1-(4-methoxyphenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P038-4891
N-[(2-fluorophenyl)methyl]-1-(4-methoxyphenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P038-4891

Molecular Formula

C23H19FN4O4 (C23 H19 FN4 O4)

Compound Name

N-[(2-fluorophenyl)methyl]-1-(4-methoxyphenyl)-3-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-[(2-fluorophenyl)methyl]-1-(4-methoxyphenyl)-3-methyl-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidine-6-carboxamide

SMILES

CN(C(c1cc(C(NCc(cccc2)c2F)=O)cnc1N1c(cc2)ccc2OC)=O)C1=O

InChI

InChI=1S/C23H19FN4O4/c1-27-22(30)18-11-15(21(29)26-12-14-5-3-4-6-19(14)24)13-25-20(18)28(23(27)31)16-7-9-17(32-2)10-8-16/h3-11,13H,12H2,1-2H3,(H,26,29)

InChI Key

VAHKYGDEHBYWRS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27559804

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.43

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.125

Distribution Coefficient, logD

3.125

Water Solubility, LogSw

-3.45

Polar Surface Area

73.070

Acid Dissociation Constant (pKa)

10.24

Base Dissociation Constant (pKb)

1.19

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

P038-4891 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Hsp90-Targeted Library (11355 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P038-4891 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P038-4891?
Check Price and Availability of P038-4891, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P038-4891 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P038-4891
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P038-4891
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P038-4891 available by request