P043-0229 Screening compound: 1-(4-fluorophenyl)-6-methoxy-N-[(3-methylphenyl)methyl]-4-oxo-1,4-dihydropyridazine-3-carboxamide

P043-0229 Screening compound: 1-(4-fluorophenyl)-6-methoxy-N-[(3-methylphenyl)methyl]-4-oxo-1,4-dihydropyridazine-3-carboxamide
P043-0229 Screening compound: 1-(4-fluorophenyl)-6-methoxy-N-[(3-methylphenyl)methyl]-4-oxo-1,4-dihydropyridazine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P043-0229
1-(4-fluorophenyl)-6-methoxy-N-[(3-methylphenyl)methyl]-4-oxo-1,4-dihydropyridazine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P043-0229

Molecular Formula

C20H18FN3O3 (C20 H18 FN3 O3)

Compound Name

1-(4-fluorophenyl)-6-methoxy-N-[(3-methylphenyl)methyl]-4-oxo-1,4-dihydropyridazine-3-carboxamide

IUPAC name

1-(4-fluorophenyl)-6-methoxy-N-[(3-methylphenyl)methyl]-4-oxo-14-dihydropyridazine-3-carboxamide

SMILES

Cc1cccc(CNC(C2=NN(c(cc3)ccc3F)C(OC)=CC2=O)=O)c1

InChI

InChI=1S/C20H18FN3O3/c1-13-4-3-5-14(10-13)12-22-20(26)19-17(25)11-18(27-2)24(23-19)16-8-6-15(21)7-9-16/h3-11H,12H2,1-2H3,(H,22,26)

InChI Key

VBQGVDXAOAFHAL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27560185

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.436

Distribution Coefficient, logD

3.435

Water Solubility, LogSw

-3.68

Polar Surface Area

59.857

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

0.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

P043-0229 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P043-0229 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P043-0229?
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What is the minimum amount of P043-0229 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P043-0229
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P043-0229
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P043-0229 available by request