P043-0846 Screening compound: 1-(4-fluorophenyl)-6-methoxy-4-oxo-N-(4-sulfamoylphenyl)-1,4-dihydropyridazine-3-carboxamide

P043-0846 Screening compound: 1-(4-fluorophenyl)-6-methoxy-4-oxo-N-(4-sulfamoylphenyl)-1,4-dihydropyridazine-3-carboxamide
P043-0846 Screening compound: 1-(4-fluorophenyl)-6-methoxy-4-oxo-N-(4-sulfamoylphenyl)-1,4-dihydropyridazine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P043-0846
1-(4-fluorophenyl)-6-methoxy-4-oxo-N-(4-sulfamoylphenyl)-1,4-dihydropyridazine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P043-0846

Molecular Formula

C18H15FN4O5S (C18 H15 FN4 O5 S)

Compound Name

1-(4-fluorophenyl)-6-methoxy-4-oxo-N-(4-sulfamoylphenyl)-1,4-dihydropyridazine-3-carboxamide

IUPAC name

1-(4-fluorophenyl)-6-methoxy-4-oxo-N-(4-sulfamoylphenyl)-14-dihydropyridazine-3-carboxamide

SMILES

COC(N(c(cc1)ccc1F)N=C1C(Nc(cc2)ccc2S(N)(=O)=O)=O)=CC1=O

InChI

InChI=1S/C18H15FN4O5S/c1-28-16-10-15(24)17(22-23(16)13-6-2-11(19)3-7-13)18(25)21-12-4-8-14(9-5-12)29(20,26)27/h2-10H,1H3,(H,21,25)(H2,20,26,27)

InChI Key

OFOOWLIGXYTLFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27560288

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.41

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.485

Distribution Coefficient, logD

1.069

Water Solubility, LogSw

-2.29

Polar Surface Area

109.138

Acid Dissociation Constant (pKa)

7.19

Base Dissociation Constant (pKb)

-0.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.60

P043-0846 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Carbonic Anhydrase II Library (4939 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with P043-0846 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P043-0846?
Check Price and Availability of P043-0846, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P043-0846 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P043-0846
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P043-0846
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P043-0846 available by request