P072-0857 Screening compound: 1-{2-oxo-2-[4-(propan-2-yl)piperazin-1-yl]ethyl}-3-phenyl-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

P072-0857 Screening compound: 1-{2-oxo-2-[4-(propan-2-yl)piperazin-1-yl]ethyl}-3-phenyl-1H,2H,3H-imidazo[4,5-b]pyridin-2-one
P072-0857 Screening compound: 1-{2-oxo-2-[4-(propan-2-yl)piperazin-1-yl]ethyl}-3-phenyl-1H,2H,3H-imidazo[4,5-b]pyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P072-0857
1-{2-oxo-2-[4-(propan-2-yl)piperazin-1-yl]ethyl}-3-phenyl-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P072-0857

Molecular Formula

C21H25N5O2 (C21 H25 N5 O2)

Compound Name

1-{2-oxo-2-[4-(propan-2-yl)piperazin-1-yl]ethyl}-3-phenyl-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

IUPAC name

1-{2-oxo-2-[4-(propan-2-yl)piperazin-1-yl]ethyl}-3-phenyl-1H2H3H-imidazo[45-b]pyridin-2-one

SMILES

CC(C)N(CC1)CCN1C(CN(c1c(N2c3ccccc3)nccc1)C2=O)=O

InChI

InChI=1S/C21H25N5O2/c1-16(2)23-11-13-24(14-12-23)19(27)15-25-18-9-6-10-22-20(18)26(21(25)28)17-7-4-3-5-8-17/h3-10,16H,11-15H2,1-2H3

InChI Key

YMEVKNBGZABORC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562000

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.46

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.825

Distribution Coefficient, logD

1.492

Water Solubility, LogSw

-1.97

Polar Surface Area

47.824

Acid Dissociation Constant (pKa)

21.44

Base Dissociation Constant (pKb)

7.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

P072-0857 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Library (67538 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with P072-0857 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P072-0857?
Check Price and Availability of P072-0857, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P072-0857 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P072-0857
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P072-0857
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P072-0857 available by request