P072-1457 Screening compound: 3-(4-fluorophenyl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

P072-1457 Screening compound: 3-(4-fluorophenyl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one
P072-1457 Screening compound: 3-(4-fluorophenyl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound P072-1457
3-(4-fluorophenyl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P072-1457

Molecular Formula

C19H19FN4O2 (C19 H19 FN4 O2)

Compound Name

3-(4-fluorophenyl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H,2H,3H-imidazo[4,5-b]pyridin-2-one

IUPAC name

3-(4-fluorophenyl)-1-[2-oxo-2-(piperidin-1-yl)ethyl]-1H2H3H-imidazo[45-b]pyridin-2-one

SMILES

O=C(CN(c1cccnc1N1c(cc2)ccc2F)C1=O)N1CCCCC1

InChI

InChI=1S/C19H19FN4O2/c20-14-6-8-15(9-7-14)24-18-16(5-4-10-21-18)23(19(24)26)13-17(25)22-11-2-1-3-12-22/h4-10H,1-3,11-13H2

InChI Key

XFHMEZFGFGSMKO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562207

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.38

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.322

Distribution Coefficient, logD

2.322

Water Solubility, LogSw

-2.59

Polar Surface Area

43.960

Acid Dissociation Constant (pKa)

21.44

Base Dissociation Constant (pKb)

2.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

P072-1457 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with P072-1457 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P072-1457?
Check Price and Availability of P072-1457, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P072-1457 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P072-1457
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P072-1457
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P072-1457 available by request