P073-0445 Screening compound: N-(2-{1-benzyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)-2-chlorobenzamide

P073-0445 Screening compound: N-(2-{1-benzyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)-2-chlorobenzamide
P073-0445 Screening compound: N-(2-{1-benzyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)-2-chlorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P073-0445
N-(2-{1-benzyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)-2-chlorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P073-0445

Molecular Formula

C22H19ClN4O2 (C22 H19 ClN4 O2)

Compound Name

N-(2-{1-benzyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)-2-chlorobenzamide

IUPAC name

N-(2-{1-benzyl-2-oxo-1H2H3H-imidazo[45-b]pyridin-3-yl}ethyl)-2-chlorobenzamide

SMILES

O=C(c(cccc1)c1Cl)NCCN(c1ncccc1N1Cc2ccccc2)C1=O

InChI

InChI=1S/C22H19ClN4O2/c23-18-10-5-4-9-17(18)21(28)25-13-14-26-20-19(11-6-12-24-20)27(22(26)29)15-16-7-2-1-3-8-16/h1-12H,13-15H2,(H,25,28)

InChI Key

HETSIMHDVRHTEE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562396

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.161

Distribution Coefficient, logD

4.161

Water Solubility, LogSw

-4.42

Polar Surface Area

52.684

Acid Dissociation Constant (pKa)

12.60

Base Dissociation Constant (pKb)

0.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

P073-0445 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with P073-0445 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P073-0445?
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What is the minimum amount of P073-0445 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P073-0445
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P073-0445
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P073-0445 available by request