P073-0494 Screening compound: N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)cyclobutanecarboxamide

P073-0494 Screening compound: N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)cyclobutanecarboxamide
P073-0494 Screening compound: N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)cyclobutanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound P073-0494
N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)cyclobutanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

P073-0494

Molecular Formula

C21H24N4O2 (C21 H24 N4 O2)

Compound Name

N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-3-yl}ethyl)cyclobutanecarboxamide

IUPAC name

N-(2-{1-[(4-methylphenyl)methyl]-2-oxo-1H2H3H-imidazo[45-b]pyridin-3-yl}ethyl)cyclobutanecarboxamide

SMILES

Cc1ccc(CN(c2c(N3CCNC(C4CCC4)=O)nccc2)C3=O)cc1

InChI

InChI=1S/C21H24N4O2/c1-15-7-9-16(10-8-15)14-25-18-6-3-11-22-19(18)24(21(25)27)13-12-23-20(26)17-4-2-5-17/h3,6-11,17H,2,4-5,12-14H2,1H3,(H,23,26)

InChI Key

KYZCBTICHDOEPR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27562427

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.728

Distribution Coefficient, logD

2.728

Water Solubility, LogSw

-2.96

Polar Surface Area

53.207

Acid Dissociation Constant (pKa)

14.60

Base Dissociation Constant (pKb)

1.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

P073-0494 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

C-Met Library (15277 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with P073-0494 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound P073-0494?
Check Price and Availability of P073-0494, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of P073-0494 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for P073-0494
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for P073-0494
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of P073-0494 available by request